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Harwell, Oxford, May 1, 2025, ����appTherapeutics Limited (����app), a platform biotech company developing novel mitochondrial-targeted persulfide modifiers, today announces the appointment of Xavier Jacq as Chief Scientific Officer (CSO).

Xavier is a world-class scientist with extensive experience in small-molecule drug development and mitochondrial biology. He was most recently CSO at Moa Technologies in Oxford. Xavier previously held scientific leadership positions at Almac and Mission Therapeutics, and project leadership positions at Kudos and Sanofi. He has been a company founder, helping raise investment, building labs and drug discovery teams from scratch, and helping companies successfully exit through acquisition.

The new CSO significantly strengthens the ����app team as it builds towards clinical candidate nomination in its lead indication of the treatment of obesity and also develops a pipeline of discrete novel persulfide modifiers for a range of degenerative diseases.

“Welcoming Xavier to ����app cements our position as the leading biotech company developing mitochondrial-targeted therapeutics,” said Jon Rees, CEO, ����app.

“����app is developing an innovative technology to restore mitochondrial metabolic pathways that are suppressed in a number of pathologies and in ageing. The prospect of being able to contribute to restoring metabolic function for patients with unmet medical needs is such an exciting opportunity that I had to join,” said Xavier Jacq, CSO, ����app. “����app is a company with an enthusiastic and experienced team. This was also an essential factor in my decision to join ����app. We now have the potential to make a significant difference a large number of patients with degenerative diseases.”